researchingrna / RNA Structure and Regulation Group : RNA

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Title	RNA Structure and Regulation Group : RNA
Description	We are the RNA structure and regulation research laboratory at the Clemson University Center for Human Genetics, headed by Dr. Lela
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RNA S&R Lackey Lab Menu Home Meet the Team Research Lab News Scroll down to content RNA Structure and Regulation Group RNA Structure and Regulation Group Messenger RNAs (mRNAs) pass along information that can be decoded to produce protein. Importantly, these same mRNAs also contain information determining when, where and how much protein to make. This regulatory information is part of the RNA and can have a huge impact on the final protein output. The RNA Structure and Regulation group looks for ways to identify regulatory elements within mRNA and understand how regulatory elements function. Some examples of common regulatory elements are upstream open reading frames within the 5′ Untranslated Region (UTR) of a mRNA, splice sites at the junction between exons and introns and polyadenylation sites within the 3′ UTR. Local RNA structure can influence the activity of nearly all regulatory elements. We are also interested in how variation in our DNA impacts RNA regulation by altering RNA

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